Course Descriptions in Biochemistry, Chemistry and Pharmacognosy
Advanced Pharmacognosy, BS736
This course builds on information provided in Pharmacognosy (BS336). A combination of lecture and "journal club" format will be used, which will relate current literature to the lecture themes. Each student will be responsible for preparing a written and oral mini-review of the literature on a topic related to the current state of knowledge in pharmacognosy.
(Prerequisite: permission of instructor)
Cell Biology Methods, BS763
The theory of methodologies and techniques commonly used in modern cell biology and biochemistry laboratory settings. Each student will be required to develop an understanding of the theory and current practice of separations and analysis of biochemical and cellular systems, including cell cultures, SDS-PAGE, affinity chromatography, HPLC analysis, cell manipulation, ELISAs, and fluorescence microscopy. The course is complementary to BS767, Cell Biology Methods Laboratory.
(Prerequisite: one semester of cell biology and biochemistry, or permission of instructor)
Current Research in Pharmacognosy, BS870
An in-depth consideration of current literature concerning the taxonomic distribution, biosynthesis, chemical synthesis, extraction, pharmacology and economic uses of substances of natural origin. Students are expected to make presentations based on the current literature.
(Prerequisite: BS236, CH343 or permission of instructor)
Heterocyclic Chemistry, CH718
A study of the major types of aromatic and nonaromatic heterocyclic compounds with a special interest in those having biochemical activity; their synthesis, physical properties, reactivity, influence on living systems, etc.
(Prerequisites: CH202 or CH212, and CH341)
Physical Biochemistry, CH727
Application of principles of thermodynamics, kinetics and quantum chemistry to biochemical systems.
(Prerequisite: CH321)
Advanced Biochemistry, CH728
Selected topics in protein structure and function, especially enzymology.
(Prerequisite: two semesters of undergraduate biochemistry)
Master's Research, CH799
Candidates for the master of science degree, specializing in chemistry, biochemistry, or pharmacognosy, are required to complete a research project under the direction of a department faculty member.
(Prerequisite: permission of program director)
Research Seminar, CH802
Graduate students present a formal seminar based on their research endeavors.
(Prerequisite: permission of program director)
Critical Evaluation of Literature, CH805
Students critique current journal articles under the mentorship of different faculty members and a course coordinator.
(Prerequisite: permission of program director)
Introduction to Research, CH878
A laboratory rotation through two seven-week chemical, biochemical or pharmacognosy research projects for
graduate students matriculated in a graduate program in the Department of Chemistry & Biochemistry.
(Prerequisite: permission of program director)
Current Literature, CH880
Chemical topics based on current literature are analyzed and presented orally and in a written precis. Writing, speech, delivery and use of visual aids are critiqued.
(Prerequisite: permission of program director)
Graduate Project, CH888
Graduate students will perform a graduate level project under the direction of an advisor. This project may take one of several forms but must include a comprehensive literature search, a written paper and an oral presentation to the graduate faculty of the department.
(Prerequisite: permission of program director)
Doctoral Research, CH899
Candidates for the Doctor of Philosophy degree, specializing
in biochemistry, are required to fulfill their research requirement
under the direction of a department faculty member.
(Prerequisite: permission of program director)
Introduction to Plant Tissue Culture, BS332
Introduction to the theory, practice and biotechnical
applications of culturing plant cells, tissues and organs.
(Prerequisites: BS104 or BS131, and CH202 or CH212)
Chemotaxonomy, BS722
Contemporary concepts of classification of plants in "chemical
families," and relationship of new classification systems to
classical taxonomy.
(Prerequisite: permission of instructor)
Plant Biochemistry, BS724
Biosynthetic mechanisms of the plant; biogenesis of alkaloids, steroids, glycosides, volatile oils, tannins, flavonoids and other plant principles.
Ethnobotany, BS728
The study of the interactions of various human cultures
with plants in the local environment. Topics on the use of
plants in medicinal, ritual, and cultural contexts by various
aboriginal cultures will be addressed.
(Prerequisite: permission of instructor)
Marine Pharmacognosy, BS737
Survey of nature and taxonomy of biotoxic marine organisms
and consideration of the chemistry and biological activity
of drugs of marine origin.
(Prerequisites: BS336, and CH202
or CH212, or permission of instructor)
Biotechnology, BS764
An in-depth study of the techniques and applications of
recombinant DNA technology with emphasis on current
literature. Students will learn techniques of recombinant DNA
technology, develop an understanding of biotechnology
industry product development, and examine ethical issues
concerning biotechnology.
(Prerequisite: one semester of
genetics and biochemistry, or permission of instructor)
Biotechnology Laboratory, BS765
This laboratory course will provide students the opportunity
to gain hands-on experience in recombinant DNA technology,
experimental design principles and data analysis.
(Pre- or co-requisites: BS764 and permission of instructor)
Biochemical Genetics, BS768
Topics of current interest in molecular biology and
molecular genetics are explored using the current
literature.
(Prerequisites: one semester each of genetics
and biochemistry, or permission of instructor)
Intermediate Organic Chemistry, CH705
Presents several topics at an intermediate level to
bridge the gap between second-year organic chemistry
and literature-based courses. Topics include nomenclature,
stereochemistry, multistep synthesis, mechanisms,
aromaticity and physical influences on reactions.
(Prerequisite: Ch202 or CH212)
Structure/Activity Relationships, CH714
Selected classes of medicinal agents are examined,
stressing general structures, synthesis, and, in particular,
the relationships between structure and pharmacological
activity.
(Prerequisites: CH212 and permission of instructor)
Chemical Synthesis Laboratory, CH716
Techniques of organic and inorganic synthesis, including
reaction control, vacuum and fractional distillation, uniform
reagent addition, controlled stirring, operation in inert
atmosphere, safe handling of toxic or unstable reagents, and
chromatographic purification.
(Prerequisites: CH212, CH214
and CH362)
Characterization of Organic Compounds, CH717
Determination of structures of organic compounds through
the use of spectroscopic as well as classical chemical
and physical techniques.
(Prerequisites: CH212, CH214
and CH362)
Heterocyclic Chemistry, CH718
A study of the major types of aromatic and nonaromatic
heterocyclic compounds with a special interest in those
having biochemical activity: their synthesis, physical
properties, reactivity, influence on living systems, etc.
(Prerequisites: CH202 or CH212, and CH341)
Chemical Kinetics, CH721
Theoretical aspects of reaction kinetics and the experimental
methods used to measure the rate of reactions.
(Prerequisite:
CH322 or permission of instructor)
Graduate Physical Chemistry, CH725
Fundamental concepts of physical chemistry, with an
emphasis on thermodynamics, chemical and phase
equilibria, solutions, etc.
(Prerequisites: MA201) and PY212)
Graduate Physical Chemistry, CH726
A continuation of CH725, with emphasis on quantum
chemistry, reaction kinetics, statistical mechanics, etc.
(Prerequisite: CH726)
Inorganic Pharmaceuticals, CH731
A study of the origins and utility of inorganic pharmaceuticals,
with emphasis on recent success in the management
of cancer and rheumatoid arthritis via transition metal
drug therapy. Future directions of inorganic pharmaceutical
research will be debated and discussed.
(Prerequisite:
CH202 or CH212. CH431 is recommended)
Analysis of Medicinals, CH761
Application of analytical methods to assay pharmaceutical
dosage forms. Development of analytical procedures for
complex pharmaceutical preparation utilizing modern
techniques.
(Prerequisites: CH361, and CH417 or CH717)
Analytical Separations Chemistry, CH762
Theory, instrumentation and practical aspects of analytical
and preparative methods of separations, including gas,
liquid and supercritical fluid chromatography, capillary
electrophoresis and separation techniques coupled and
mass spectrometry.
(Prerequisite: CH361 or permission
of instructor)
Applied Spectroscopy, CH767
A practical approach to the application of spectroscopic
techniques such as IR, UV/Vis, NMR and mass spec.
to problems in biochemistry, chemistry, pharmaceutics,
pharmacognosy and natural products chemistry.
(Prerequisite: CH362 or permission of instructor)
Chemistry of Medicinals, CH811
Synthetic and natural medicinal agents. Synthetic procedures
for production of various classes of medicinal compounds,
as well as the design of potential drug substances.
(Prerequisites: CH404 and permission of instructor)
Special Topics in Organic Chemistry, CH813
Topics of current interest in organic chemistry are discussed,
with detailed treatment of topics not ordinarily included in
a classical course. Students are expected to keep abreast
of current literature.
(Prerequisite: permission of instructor)
Special Topics in Biochemistry, CH841
Topics of current interest in the biochemical sciences.
Detailed treatment of topics not ordinarily included in a
classical course. Students are expected to keep abreast
of current literature.
(Prerequisite: permission of instructor)
Lipoprotein Metabolism, CH844
Consideration of intercellular and intracellular transport and metabolism of cholesterol and triacylglycerols at the molecular level, as well as the relationship between lipoprotein metabolism and heart disease.
Special Topics in Analytical Chemistry, CH863
Topics of current interest in analytical chemistry. Detailed
treatment of topics not ordinarily included in a classical
course. Students are expected to keep abreast of current
literature.
(Prerequisite: permission of instructor)
Special Topics in Inorganic Chemistry, CH864
Topics of current interest in inorganic chemistry. Detailed
treatment of topics not ordinarily included in a classical
course. Students are expected to keep abreast of current
literature.
(Prerequisite: permission of instructor)
Special Topics in Pharmacognosy, CH871
Topics of current interest in pharmacognosy. Students
are expected to keep abreast of the current literature.
(Prerequisites: BS236 and permission of instructor)
Special Topics in Physical Chemistry, CH892
Topics of current interest in physical chemistry. Detailed
treatment of topics not ordinarily included in a classical
course. Students are expected to keep abreast of current
literature.
(Prerequisite: permission of instructor)
Statistics for Research, ST704
Statistical inference on two samples, design of experiments,
repeated measures, analysis of covariance, multiple
regression, categorical data analysis and factor analysis.
(Prerequisite: ST310 or permission of instructor)
